In the last decade, in Italy, in the context of the educational research, an interesting debate has been opened about the use of space in didactics, in agreement with the European directives. Space factor, although repeatedly discussed, in the field of educational research, was re-examined because it contributes to the creation of inclusive educational environments and setting in accordance with students educational needs. Nowadays, the design of the class should take account of paradigms of design for all and inclusive design for learning to promote a context-oriented teaching model. Act of teaching in a context-oriented model is focused not only about the interaction between teacher and their Students, but also on the environment when happens the teaching-learning process. Organization of the class environments and the learning context is important for an educational approach, which reduces the current transmission approach and increases each potential knowledge through didactic transposition contextualized in an appropriate environment. A Necessity of new studies on space theme in teaching it was appropriate, not only for this paradigm shift (context-oriented model approach) but also for a large number of new technologies and new types of furniture, on the market, that can be used in a classroom. In parallel, the evolution of studies in bio-education and neuro-didactic related to the teaching-learning process, open new interpretive scenarios in this process and during the act of teaching; both in phase of realization of a school environment and during the activities carried out daily in the classroom. In particular, the restructuring of the spaces can be studied based on scientific literature and due to application of a simplex education model.

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